Toward in vivo disease diagnosis and treatment using DNA
by Yuriy Brun, Manoj Gopalkrishnan
Abstract:
We propose a technique to diagnose and treat individual cells in the human body. A virus-like system delivers a copy of a diagnosis and treatment DNA complex to each cell. The complex determines whether the cell has a specific disease based on the presence or absence of indicator mRNA molecules and, if the diagnosis is positive, releases a proper drug for treatment. As a tool for the diagnosis and treatment system, we develop a DNA implementation of an arbitrary finite state machine.
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Citation:
Yuriy Brun and Manoj Gopalkrishnan, Toward in vivo disease diagnosis and treatment using DNA, in Proceedings of the 2006 International Conference on Bioinformatics & Computational Biology (BIOCOMP), pp. 182–186.
Bibtex:
@inproceedings{Brun06biocomp,
  author = {Yuriy Brun and Manoj Gopalkrishnan},
  title =
  {\href{http://people.cs.umass.edu/brun/pubs/pubs/Brun06biocomp.pdf}{Toward in
  vivo disease diagnosis and treatment using {DNA}}},
  booktitle = {Proceedings of the 2006 International Conference on
  Bioinformatics \& Computational Biology (BIOCOMP)},
  venue = {BIOCOMP},
  address = {Las Vegas, {NV}, {USA}},
  month = {June},
  date = {26--29},
  year = {2006},
  pages = {182--186},
  isbn = {1-60132-002-7},

  abstract = {We propose a technique to diagnose and treat individual cells in
  the human body. A virus-like system delivers a copy of a diagnosis and
  treatment DNA complex to each cell. The complex determines whether the cell
  has a specific disease based on the presence or absence of indicator mRNA
  molecules and, if the diagnosis is positive, releases a proper drug for
  treatment. As a tool for the diagnosis and treatment system, we develop a DNA
  implementation of an arbitrary finite state machine.}
}