by Yuriy Brun, Manoj Gopalkrishnan, Dustin Reishus, Bilal Shaw, Nickolas Chelyapov and Leonard Adleman
Abstract:
DNA complexes, like the double crossover, are used as building blocks for the assembly of higher-order structures. Currently, the number of experimentally proven reliable complexes is small. We have begun work on expanding the collection of such complexes. Here we report on our design concepts and initial experiments. In particular, we present experimental evidence of two new complexes: quadruple crossovers and triangles. In principle, quadruple crossovers can be extended to three-dimensional, space-filling lego brick complexes, while triangles are capable of hexagonally tiling the plane.
Citation:
Yuriy Brun, Manoj Gopalkrishnan, Dustin Reishus, Bilal Shaw, Nickolas Chelyapov, and Leonard Adleman, Building blocks for DNA self-assembly, in Proceedings of the 1st Foundations of Nanoscience: Self-Assembled Architectures and Devices (FNANO), 2004, pp. 2–15.
Bibtex Entry:
@inproceedings{Brun04fnano,
author = {Yuriy Brun and Manoj Gopalkrishnan and Dustin Reishus and Bilal
Shaw and Nickolas Chelyapov and Leonard Adleman},
title =
{Building
blocks for {DNA} self-assembly},
booktitle = {Proceedings of the 1st Foundations of Nanoscience:
Self-Assembled Architectures and Devices (FNANO)},
venue = {FNANO},
address = {Snowbird, {UT}, {USA}},
month = {April},
date = {21--23},
year = {2004},
pages = {2--15},
abstract = {DNA complexes, like the double crossover, are used as building
blocks for the assembly of higher-order structures. Currently, the number of
experimentally proven reliable complexes is small. We have begun work on
expanding the collection of such complexes. Here we report on our design
concepts and initial experiments. In particular, we present experimental
evidence of two new complexes: quadruple crossovers and triangles. In
principle, quadruple crossovers can be extended to three-dimensional,
space-filling lego brick complexes, while triangles are capable of hexagonally
tiling the plane.}
}