Building blocks for DNA self-assembly
by Yuriy Brun, Manoj Gopalkrishnan, Dustin Reishus, Bilal Shaw, Nickolas Chelyapov, Leonard Adleman
Abstract:
DNA complexes, like the double crossover, are used as building blocks for the assembly of higher-order structures. Currently, the number of experimentally proven reliable complexes is small. We have begun work on expanding the collection of such complexes. Here we report on our design concepts and initial experiments. In particular, we present experimental evidence of two new complexes: quadruple crossovers and triangles. In principle, quadruple crossovers can be extended to three-dimensional, space-filling lego brick complexes, while triangles are capable of hexagonally tiling the plane.
Citation:
Yuriy Brun, Manoj Gopalkrishnan, Dustin Reishus, Bilal Shaw, Nickolas Chelyapov, and Leonard Adleman, Building blocks for DNA self-assembly, in Proceedings of the 1st Foundations of Nanoscience: Self-Assembled Architectures and Devices (FNANO), 2004, pp. 2–15.
Bibtex:
@inproceedings{Brun04fnano,
  author = {Yuriy Brun and Manoj Gopalkrishnan and Dustin Reishus and Bilal
  Shaw and Nickolas Chelyapov and Leonard Adleman},
  title =
  {\href{http://people.cs.umass.edu/brun/pubs/pubs/Brun04fnano.pdf}{Building
  blocks for {DNA} self-assembly}},
  booktitle = {Proceedings of the 1st Foundations of Nanoscience:
  Self-Assembled Architectures and Devices (FNANO)},
  venue = {FNANO},
  address = {Snowbird, {UT}, {USA}},
  month = {April},
  date = {21--23},
  year = {2004},
  pages = {2-15},

  abstract = {DNA complexes, like the double crossover, are used as building
  blocks for the assembly of higher-order structures. Currently, the number of
  experimentally proven reliable complexes is small. We have begun work on
  expanding the collection of such complexes. Here we report on our design
  concepts and initial experiments. In particular, we present experimental
  evidence of two new complexes: quadruple crossovers and triangles. In
  principle, quadruple crossovers can be extended to three-dimensional,
  space-filling lego brick complexes, while triangles are capable of hexagonally
  tiling the plane.}
}